Job Description
Overview:
Position Title: Analyst I
Business Title: Chemist – RNA Synthesis
Department: ATL
Location: Indianapolis, IN
Reports to: Manager
FLSA: Non-Exempt
Hours Worked: Monday through Friday, forty hours per week.
However, must be flexible to meet the needs of the department and complete other projects as assigned.
Position Summary:
The
Chemist is responsible for the synthesis and downstream processing of oligo synthesis using various analytical techniques. AKTA, LC-MS, UPLC, LTQ, QDA analytical instruments are used.
Duties and Responsibilities:
- Downstream processing of synthetic compounds (purification and buffer exchange)
- Carefully prepare laboratory samples from stock/inventory for biological testing
- Maintain accurate and careful records
- Organize inventory of samples
- Synthesis of oligonucleotides on AKTA oligo pilot for solid-phase oligonucleotide synthesis
- Downstream processing of processing of synthetic compounds (purification and buffer exchange)
- Carefully prepare laboratory samples from stock/inventory for biological testing
- Use of general laboratory equipment including but not limited to pipettors, centrifuges, incubators, biological safety cabinets and balances
- Instrumentation for methods and techniques described may include AKTA, LC-MS, UPLC, LTQ, QDA, Nanodrop, etc.
- Data analysis and troubleshooting
- Lab experience with solution preparation, separation, quantification, synthesis methodologies for DNA/RNA, proteins, oligonucleotides, etc.
- Software includes instrument-specific for capturing and analyzing data, Microsoft Office (Word, Excel, PowerPoint, Outlook, Teams/Sharepoint, etc), LIMS, electronic laboratory notebooks, etc.
- Detailed record keeping of daily experiments in ELNs
- General Lab Maintenance
- Follow the guidelines set forth with clients and Company Quality, Health, Safety, Security and Environmental policies and procedures.
- Comply with clients’ and Company management systems in accordance with appropriate regulatory agencies.
- Perform other essential tasks projects and responsibilities as required.
- Other duties as defined by Manager, department needs and workload
Skills & Proficiencies:
- Demonstrated productivity in chemical or biological laboratory setting
- Experience reading and understanding scientific data
- Familiarity with scientific instruments and laboratory techniques
- Experience with RNA handling or isolation
- Experience with nucleotide, nucleoside or oligonucleotide synthesis
- Familiar with dilution and concentration calculations
- Strong organizational skills
- Strong written and oral communication skills
- Confident, execution-focused, and team oriented with a desire to thrive in a fast-paced growing environment
- Written and verbal communication skills including the ability to communicate effectively in a group setting, with colleagues and clients
- Ability to perform multiple tasks
- Ability to organize and prioritize workload to meet or exceed deadlines
- Individual and Team work ethic
- Proficiency with Windows, Word & Excel
- Attention to detail
- Positive attitude, self-motivated, high level of engagement
- Adheres to company values
Education and Experience:
- Degree requirement: Bachelor's Degree in Chemistry, Biochemistry, or closely related field
- Minimum of one (1) year of experience in a chemistry/biology lab setting
An equivalent combination of education and experience may be accepted in lieu of above.
